Amphetamines, Urine

Specimen Tube Type Transport

Urine Container

Summary Test Name

Amphetamines, Urine

Specimen Preparation Outreach

Refrigerate until courier pickup

Specimen Stability

5 days refrigerated

Minimum Volume

10 ml in urine container

Specimen Transport

Refrigerate

Stat Availability

24 hours a day, seven days a week

Test Turnaround Time Routines And Stats

4 hours / 2 hours

Reference Value

None detected

Additional Test Information

AMPHETAMINE

ASSAY CUTOFF:  ≥1000 ng/mL

ANALYTICAL SPECIFICITY:

Compound	ng/mL Equivalent to 1000 ng/mL d‑methamphetamine	Approx. Percent Cross-reactivity
± MDMAd	509	197
PMMAn	690	145
PMAm	908	110
± MDAe	771	130
d‑Amphetamine	981	102 f
d‑Methamphetamine	998	100
± MBDB HClg	1175	85
± MDEAh	1553	64
± BDB HCli	2420	41
Trazodone metabolite: mCPPj	5478	18
1‑Methyl‑3‑phenylpropylaminek	5116	20
l‑Methamphetamine	8748	11
l‑Amphetamine	24220	4
Dimethylamylaminel	100735	0.99
Phendimetrazine	138504	0.72
Phentermine	238663	0.42
Ranitidine	257561	0.39
d‑Pseudoephedrine	261780	0.38
Tyramine	284091	0.35
l‑Ephedrine	308642	0.32
d,l‑Phenylpropanolamine HCl	606061	0.17
d‑Ephedrine	657895	0.15

 

^{d) d,l‑3,4‑Methylenedioxymethamphetamine}

^{e) d,l‑3,4‑Methylenedioxyamphetamine}

^{f) Representative data from multiple lots demonstrate cross-reactivity in the range from approximately 75‑125 %}

^{g) d,l‑N‑Methyl‑1‑(3,4‑methylenedioxyphenyl)‑2‑butamine hydrochloride}

^{h) d,l‑3,4‑Methylenedioxyethylamphetamine}

^{i) d,l‑3,4‑Methylenedioxyphenyl‑2‑butamine hydrochloride}

^{j) 1‑(3‑Chlorphenyl)piperazine}

^{k) APB, metabolite of Labetalol}

^{l) 4‑Methylhexan‑2‑amine, DMAA}

^{m) para-Methoxyamphetamine}

^{n) para-Methoxymethamphetamine}

Lisdexamfetamine is a pharmacologically inactive prodrug of d‑amphetamine. After oral ingestion, lisdexamfetamine is converted to l‑lysine and active d‑amphetamine which may cause a positive test result with this assay.¹⁰